• Home
  • About us
  • Contact Us
  • Advertise
  • Media Kit 2023
  • Editorial Calendar
  • Events
  • Comments
  • Posts
Health Care Asia LogoHealth Care Asia Logo
HCA Twitter HCA Meta
  • Home
  • About us
  • Contact Us
  • Advertise
  • Media Kit 2023
  • Editorial Calendar
  • Events

Physical activity found to protect against ageing and insulin resistance

December 20, 2021
Physical activity found to protect against ageing and insulin resistance

Scientists from Monash University, Australia, have discovered a new enzyme produced through exercise that might help stave off declining metabolic health in older people. Physical inactivity in aging populations leads to the development of insulin resistance: when the body’s cells do not respond well to insulin nor take up glucose as they should, leaving it to build up in the blood instead. Insulin resistance is a major risk factor for type 2 diabetes and is also associated with obesity.

As for the biological mechanisms related to insulin resistance, the scientists were able to show that physical activity promotes metabolic health via the production of reactive oxygen species (ROS) in skeletal muscle. ROS production in skeletal muscle declines with age and is implicated in the development of insulin resistance.

In mouse experiments, newly discovered enzyme called NOX4 was observed to be at the center of this process. NOX4 levels were heightened after exercise, which in turn boosted levels of ROS and protected the mice from developing insulin resistance. This was also true of aging mice and mice with diet-induced obesity.

In addition, the experiments showed that concentrations of NOX4 in skeletal muscle are directly related to aging and a decline in insulin sensitivity. The scientists said NOX4 has the potential to be targeted with drugs that boost its activity and maintain metabolic health in aging people. They also imagine that the solution could be found in nature, though there will be much work to do before this can be translated into therapeutics.

Category: Features, Wellness and Complementary Therapies

Email Facebook Google StumbleUpon Tumblr Twitter

Subscribe

If you enjoyed this article, subscribe to receive more just like it.

Privacy guaranteed. We never share your info.
Subscribe via RSS Feed Follow Us on Twitter Connect on Facebook

Comments are closed.

« Thomson X, WhiteCoat to launch first-of-its-kind mobile app for women and children
Ultrasound could treat psychiatric disorders with adaptive behavioural pattern »
2023 MJN Media Kit
Subscribe to HCA for exclusive updates

Sponsored Content

6 Ways to improve your hearing and prevent hearing loss

6 Ways to improve your hearing and prevent hearing loss

Caring for your hearing health is essential regardless of your age. Not only does it reduce the risk of suffering from irreversible hearing loss... Read More

Top Viewed News

Sunway Sanctuary upscale senior living facility to open in 2023 in Kuala Lumpur

Sunway Sanctuary upscale senior living facility to open in 2023 in Kuala Lumpur

Sunway Healthcare Group (Sunway Healthcare) is set to launch its flagship senior living residence in response to increasing... Read More

A look into type 1 diabetes

A look into type 1 diabetes

The World Health Organisation (WHO) has mentioned that diabetes claims about three lives every minute worldwide – to narrow it down diabetes has been found to affect over 1 in 5 Malaysians... Read More

Regular breast cancer screening and self-examination helps your chances of survival

Regular breast cancer screening and self-examination helps your chances of survival

The prevalence of breast cancer is expected to cause more than 2.5 million deaths between 2020 and 2040, if nothing is done to avert it... Read More

Identifying childhood diabetes

Identifying childhood diabetes

Type 1 diabetes mellitus mostly afflicts young children – it is apparently the most common form of childhood diabetes in Malaysia... Read More

Free counters!

2023 -2024 Exhibitions



2023 Events


4-6 October
Medical Device Development (MEDIX)- Osaka
INTEX, Osaka
www.japan-mfg-kansai.jp


9-11 October
Saudi International Pharma Expo
Riyadh International Convention and Exhibition Center
www.saudipharmaexpo.com


9-11 October
Saudi International MedLab Expo
Riyadh International Convention and Exhibition Center
www.saudimedlabexpo.com


10-11 October
AI Asia Expo Philippines
Marriott Grand Ballroom Convention Center, Manila
www.aiasiaexpo.com


19-21 October
Health Asia
Karachi Expo Center, Pakistan
www.health-asia.com


3-4 November
Eldercare Exhibition and Conference Asia (ELDEX Asia 2023)
Suntex Singapore Exhibition and Convention Centre
www.eldexasia.com


28 November 2023 @ 9:00 am to 29 November 2023 @ 5:30 pm
Hospital @ Home Asia
Singapore
www.hospitalmanagementasia.com


2024 Events


11-13 September
Medical Fair Asia
Marina Bay Sands, Singapore
www.medicalfair-asia.com


Tweets by @healthcareasia

© 2023 Healthcare Asia Daily News | Asia's Leading News and Information Source on Healthcare and Medical Industry, Medical Technology, Healthcare Business and R&D, Healthcare Events. Online since 2010. All rights reserved