• Home
  • About us
  • Contact Us
  • Advertise
  • Media Kit 2023
  • Editorial Calendar
  • Events
  • Comments
  • Posts
Health Care Asia LogoHealth Care Asia Logo
HCA Twitter HCA Meta
  • Home
  • About us
  • Contact Us
  • Advertise
  • Media Kit 2023
  • Editorial Calendar
  • Events

Stem cell technique to “revolutionise” regenerative medicine

April 21, 2022
Stem cell technique to “revolutionise” regenerative medicine

Transient reprogramming of stem cells may hold the answer to rejuvenating aging cells without compromising on their function, claim researchers from the Epigenetics research programme at Babraham Institute, UK. The technique, which would normally take around 50 days, instead involves partial reprogramming of cells – finessed by the Babraham researchers, the new technique exposes cells to important developmental molecules called Yamanaka factors and can be completed in under two weeks.

As we age, our cells’ ability to function declines and the genome accumulates marks of ageing. Enter regenerative biology, which aims to repair or replace ageing cells. One of the most important tools in regenerative biology is the ability to create “induced” stem cells, a process that eventually erases some of the marks that make cells specialised. In theory, induced stem cells have the potential to become any cell type, but scientists aren’t yet able to reliably recreate the necessary conditions.

However, in 2007, Shinya Yamanaka won a Nobel Prize for successfully turning normal cells, which have a specific function, into stem cells. Further tweaks to the “maturation phase transient reprogramming” enabled researchers to find the precise balance between reprogramming cells: making them biologically younger, while still being able to retain their specialised cell function.

As explained by Dr. Diljeet Gill, a postdoc in Wolf Reik’s lab at the Institute, “Our understanding of ageing on a molecular level has progressed over the last decade, giving rise to techniques that allow researchers to measure age-related biological changes in human cells. We were able to apply this to our experiment to determine the extent of reprogramming our new method achieved.”

Genome analysis showed that cells had regained markers characteristic of skin cells (fibroblasts), confirmed by observing collagen production in the reprogrammed cells. Fibroblasts produce collagen, a molecule found in bones, skin tendons and ligaments, helping provide structure to tissues and heal wounds. The rejuvenated fibroblasts produced more collagen proteins compared to control cells that did not undergo the reprogramming process, and also moved into areas that needed wound healing.

The researchers believe the novel technique may provide youthful treatment to other age-related diseases and symptoms as well.

Read: Singapore’s SCG acquires key stem cell manufacturing technology for cancer treatment

Health Care Asia Home Health Care Asia

Tags: cells, regenerative medicine, revolutionise, stem cell

Category: Education, Features

Email Facebook Google StumbleUpon Tumblr Twitter

Subscribe

If you enjoyed this article, subscribe to receive more just like it.

Privacy guaranteed. We never share your info.
Subscribe via RSS Feed Follow Us on Twitter Connect on Facebook

Comments are closed.

« Alpaca nanobodies successfully treats rheumatoid arthritis and gout
Faster walking pace beneficial to biological aging »
2023 MJN Media Kit
Subscribe to HCA for exclusive updates

Sponsored Content

6 Ways to improve your hearing and prevent hearing loss

6 Ways to improve your hearing and prevent hearing loss

Caring for your hearing health is essential regardless of your age. Not only does it reduce the risk of suffering from irreversible hearing loss... Read More

Top Viewed News

Sunway Sanctuary upscale senior living facility to open in 2023 in Kuala Lumpur

Sunway Sanctuary upscale senior living facility to open in 2023 in Kuala Lumpur

Sunway Healthcare Group (Sunway Healthcare) is set to launch its flagship senior living residence in response to increasing... Read More

A look into type 1 diabetes

A look into type 1 diabetes

The World Health Organisation (WHO) has mentioned that diabetes claims about three lives every minute worldwide – to narrow it down diabetes has been found to affect over 1 in 5 Malaysians... Read More

Regular breast cancer screening and self-examination helps your chances of survival

Regular breast cancer screening and self-examination helps your chances of survival

The prevalence of breast cancer is expected to cause more than 2.5 million deaths between 2020 and 2040, if nothing is done to avert it... Read More

Identifying childhood diabetes

Identifying childhood diabetes

Type 1 diabetes mellitus mostly afflicts young children – it is apparently the most common form of childhood diabetes in Malaysia... Read More

Free counters!

2023 -2024 Exhibitions



2023 Events


4-6 October
Medical Device Development (MEDIX)- Osaka
INTEX, Osaka
www.japan-mfg-kansai.jp


9-11 October
Saudi International Pharma Expo
Riyadh International Convention and Exhibition Center
www.saudipharmaexpo.com


9-11 October
Saudi International MedLab Expo
Riyadh International Convention and Exhibition Center
www.saudimedlabexpo.com


10-11 October
AI Asia Expo Philippines
Marriott Grand Ballroom Convention Center, Manila
www.aiasiaexpo.com


19-21 October
Health Asia
Karachi Expo Center, Pakistan
www.health-asia.com


3-4 November
Eldercare Exhibition and Conference Asia (ELDEX Asia 2023)
Suntex Singapore Exhibition and Convention Centre
www.eldexasia.com


28 November 2023 @ 9:00 am to 29 November 2023 @ 5:30 pm
Hospital @ Home Asia
Singapore
www.hospitalmanagementasia.com


2024 Events


11-13 September
Medical Fair Asia
Marina Bay Sands, Singapore
www.medicalfair-asia.com


Tweets by @healthcareasia

© 2023 Healthcare Asia Daily News | Asia's Leading News and Information Source on Healthcare and Medical Industry, Medical Technology, Healthcare Business and R&D, Healthcare Events. Online since 2010. All rights reserved