Sputnik Light in mix-and-match approach with Chinese COVID vaccines

February 24, 2022
Sputnik Light in mix-and-match approach with Chinese COVID vaccines

Chinese regulatory authorities have approved the mixing of its Sinovac and Sinopharm COVID-19 (COVID) vaccines with a different booster shot in the hopes of creating a stronger and more durable immunity, including against Omicron. With the new approval, the Russian one-shot Sputnik Light vaccine (the first component of Sputnik V) is set to become a universal booster for those vaccinated with the Chinese vaccines in other countries around the world, to strengthen and lengthen their protection against COVID.

Already, the Sputnik Light vaccine has shown strong results used as a booster in mix & match trials: a study conducted in Argentina on Sputnik Light in combination with other vaccines has shown that antibody and T-cells response elicited by Sputnik Light as a booster to inactivated Sinopharm vaccine is 10 times higher, compared to just two shots of Sinopharm.

The study also has demonstrated that each “vaccine cocktail” combination – Sputnik Light with other vaccines like Moderna, AstraZeneca and Cansino – had provided a higher antibody titre on the 14th day after administering a second dose when compared to original homologous (same vaccine as first and second dose) regimens of each of the vaccines. Most importantly, the use of Sputnik Light in combination(s) with all other vaccines showed high safety profile with no serious adverse events following the vaccination.

According to global studies and real-world data, Sputnik V and Sputnik Light can be stored in a conventional refrigerator for up to 6 months, and are available even in remote territories, without any need to invest in additional cold-chain infrastructure.

To date, Sputnik Light has been approved in more than 30 countries with a total population of over 2.5 billion and Sputnik V has been approved in 71 countries with a total population of over 4 billion people.

Sputnik V is said to create a stronger and longer lasting immune response against COVID (including the Omicron variant) than many other vaccines; a Sputnik Light booster further strengthens it. The Russian vaccines have been developed using a safe technology that has been widely studied for more than 30 years and have not been associated with rare, serious side effects such as myocarditis or pericarditis.

Category: Features, Pharmaceuticals

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