Moles on your right arm can gauge skin cancer risk

October 21, 2015

Researchers at King’s College London found that having more than 11 moles on your right arm is a red flag for skin cancer.

Scientists found that females with more than seven moles on their right arm had nine times the risk of having more than 50 on the whole body and those with more than 11 on their right arm were more likely to have over 100 on their body in total, meaning they were at a higher risk of developing a melanoma.

Naevus (mole) count is one of the most important markers of risk for skin cancer despite only 20 to 40% of melanoma arising from pre-existing moles. The risk is thought to increase by two to four percent per additional mole on the body, but counting the total number on the entire body can be time consuming in a primary care setting.

Previous studies on a smaller scale have attempted to identify mole count on certain body sites as a proxy to accurately estimate the number on the body as a whole and found that the arm was the most predictive.

The researchers used data from 3594 female Caucasian twins between January 1995 and December 2003 as part of the TwinsUK study protocol. Twins underwent a skin examination including recording skin type, hair and eye colour and freckles as well as mole count on 17 body sites performed by trained nurses. This was then replicated in a wider sample of male and female participants from a UK melanoma case control study published previously.

Scientists also found that the area above the right elbow was particularly predictive of the total body count of moles. The legs were also strongly associated with the total count as well as the back area in males.

Lead author, Simone Ribero of the Department of Twin Research & Genetic Epidemiology said: ‘This study follows on from previous work to identify the best proxy site for measuring the number of moles on the body as a whole. The difference here is that it has been done on a much larger scale in a healthy Caucasian population without any selection bias and subsequently replicated in a case control study from a similar healthy UK population, making the results more useful and relevant for GPs.

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